|
rs121913483
|
|
|
0.820 |
GeneticVariation |
BEFREE |
PATIENT SUMMARY: We propose that APOBEC-mediated mutagenesis can generate clinically relevant driver mutations even within suboptimal motifs, such as in the case of FGFR3 S249C, one of the most common mutations in bladder cancer.
|
30975452 |
2019 |
|
rs2294008
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Our meta-analysis supports that the PSCA gene variant rs2294008 polymorphism might contribute to individual susceptibility to bladder cancer.
|
31008939 |
2019 |
|
rs2294008
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Cumulative evidence of an association was graded as strong for rs2294008 [odds ratio (OR) = 1.32, P = 5.1 × 10-33], rs2976392 (OR = 1.29, P = 1.8 × 10-8), rs9297976 (OR = 0.75, P = 1.4 × 10-7), rs2976391 (OR = 1.38, P = 6.1 × 10-5) and rs138377917 (OR = 0.53, P = 0.008) with gastric cancer, rs2294008 with bladder cancer (OR = 1.15, P = 8.0 × 10-19), gastritis (OR = 1.35, P = 1.2 × 10-5), duodenal ulcer (OR = 0.68, P = 2.4 × 10-57) and gastric ulcer (OR = 0.88, P = 1.7 × 10-7).
|
30407486 |
2019 |
|
rs10936599
|
|
|
0.720 |
GeneticVariation |
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
rs1695
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Glutathione S-Transferase Pi 1 (GSTP1) Gene 313 A/G (rs1695) polymorphism is associated with the risk of urinary bladder cancer: Evidence from a systematic review and meta-analysis based on 34 case-control studies.
|
31454540 |
2019 |
|
rs833052
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our meta-analysis suggested that rs3025039 (C > T), rs833052 (C > A) and rs25648 (C > T) polymorphisms of VEGF gene increased susceptibility to BCa risk.
|
30849545 |
2019 |
|
rs833052
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The VEGF gene rs3025039C/T and rs833052C/A variants may contribute to the risk of developing BCa, especially in Asian descendants.
|
30609111 |
2019 |
|
rs25648
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our meta-analysis suggested that rs3025039 (C > T), rs833052 (C > A) and rs25648 (C > T) polymorphisms of VEGF gene increased susceptibility to BCa risk.
|
30849545 |
2019 |
|
rs699947
|
|
|
0.030 |
GeneticVariation |
BEFREE |
As to ethnicity subgroup analysis, rs699947 and rs3025039 polymorphisms were thought as a risk factor for BCa risk in Asian population, while a decreased association was revealed between rs699947 (C > A) A-allele and BCa risk in African population under dominant, recessive, homozygous, heterozygous and allele contrast genetic models.
|
30849545 |
2019 |
|
rs217727
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results provided the evidence that rs217727 in H19 was associated with elevated risk of bladder cancer, which may be a potential biomarker for predicting bladder cancer susceptibility.
|
29595036 |
2019 |
|
rs3025039
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The VEGF gene rs3025039C/T and rs833052C/A variants may contribute to the risk of developing BCa, especially in Asian descendants.
|
30609111 |
2019 |
|
rs3025039
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our meta-analysis suggested that rs3025039 (C > T), rs833052 (C > A) and rs25648 (C > T) polymorphisms of VEGF gene increased susceptibility to BCa risk.
|
30849545 |
2019 |
|
rs3834129
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Caspase-8 rs3834129 genotypes play a minor role in the personal susceptibility to bladder cancer in Taiwan.
|
31519577 |
2019 |
|
rs12921862
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>AXIN1</i> gene polymorphisms might implicate in BC risk, and rs12921862 could be a potential forecasting factor for prognosis of BC patients.
|
31143301 |
2019 |
|
rs138377917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cumulative evidence of an association was graded as strong for rs2294008 [odds ratio (OR) = 1.32, P = 5.1 × 10-33], rs2976392 (OR = 1.29, P = 1.8 × 10-8), rs9297976 (OR = 0.75, P = 1.4 × 10-7), rs2976391 (OR = 1.38, P = 6.1 × 10-5) and rs138377917 (OR = 0.53, P = 0.008) with gastric cancer, rs2294008 with bladder cancer (OR = 1.15, P = 8.0 × 10-19), gastritis (OR = 1.35, P = 1.2 × 10-5), duodenal ulcer (OR = 0.68, P = 2.4 × 10-57) and gastric ulcer (OR = 0.88, P = 1.7 × 10-7).
|
30407486 |
2019 |
|
rs1805105
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data revealed that three tag SNPs were associated with an increased risk of BC (rs12921862: <i>P</i> < 0.001, OR (95%CI) = 4.61 (3.13-6.81); rs1805105: <i>P</i> = 0.046, OR (95%CI) = 1.35 (1.00-1.82); and rs370681: <i>P</i> = 0.004, OR (95%CI) = 1.56 (1.15-2.10)).
|
31143301 |
2019 |
|
rs2067079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The T G haplotype (rs2067079 and rs6790) increased the risk of bladder cancer in the assessed population (OR (95% CI) = 1.73 (1.18-2.56), adjusted P value = 0.02).
|
31250374 |
2019 |
|
rs2073859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-Restriction Fragment Length Polymorphism (RFLP) was used to genotype LIMK2 SNP rs2073859 and multivariate logistic regression applied to assess the relationship between allele frequency and clinical features in 139 BC patients.
|
30006972 |
2019 |
|
rs2278329
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients with bladder cancer and controls did not differ significantly in terms of genotype frequencies and allele frequency distribution of rs2278329 (P = 0.77, OR = 0.97) and rs2292016 (P = 0.39, OR = 1.20) respectively.
|
30755233 |
2019 |
|
rs2292016
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients with bladder cancer and controls did not differ significantly in terms of genotype frequencies and allele frequency distribution of rs2278329 (P = 0.77, OR = 0.97) and rs2292016 (P = 0.39, OR = 1.20) respectively.
|
30755233 |
2019 |
|
rs2293607
|
|
|
0.010 |
GeneticVariation |
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
rs2735971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between lncRNA H19 (rs217727, rs2735971 and rs3024270) polymorphisms and the risk of bladder cancer in Chinese population.
|
29595036 |
2019 |
|
rs2976391
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cumulative evidence of an association was graded as strong for rs2294008 [odds ratio (OR) = 1.32, P = 5.1 × 10-33], rs2976392 (OR = 1.29, P = 1.8 × 10-8), rs9297976 (OR = 0.75, P = 1.4 × 10-7), rs2976391 (OR = 1.38, P = 6.1 × 10-5) and rs138377917 (OR = 0.53, P = 0.008) with gastric cancer, rs2294008 with bladder cancer (OR = 1.15, P = 8.0 × 10-19), gastritis (OR = 1.35, P = 1.2 × 10-5), duodenal ulcer (OR = 0.68, P = 2.4 × 10-57) and gastric ulcer (OR = 0.88, P = 1.7 × 10-7).
|
30407486 |
2019 |
|
rs2976392
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cumulative evidence of an association was graded as strong for rs2294008 [odds ratio (OR) = 1.32, P = 5.1 × 10-33], rs2976392 (OR = 1.29, P = 1.8 × 10-8), rs9297976 (OR = 0.75, P = 1.4 × 10-7), rs2976391 (OR = 1.38, P = 6.1 × 10-5) and rs138377917 (OR = 0.53, P = 0.008) with gastric cancer, rs2294008 with bladder cancer (OR = 1.15, P = 8.0 × 10-19), gastritis (OR = 1.35, P = 1.2 × 10-5), duodenal ulcer (OR = 0.68, P = 2.4 × 10-57) and gastric ulcer (OR = 0.88, P = 1.7 × 10-7).
|
30407486 |
2019 |
|
rs3024270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between lncRNA H19 (rs217727, rs2735971 and rs3024270) polymorphisms and the risk of bladder cancer in Chinese population.
|
29595036 |
2019 |